Company Filing History:
Years Active: 1999-2002
Title: Innovations and Contributions of Miguel A Pappolla
Introduction
Miguel A Pappolla is a notable inventor based in Mobile, Alabama. He has made significant contributions to the field of medical science, particularly in the treatment of diseases related to amyloidosis and oxidative stress. With a total of three patents to his name, Pappolla's work has the potential to impact the lives of many individuals suffering from these conditions.
Latest Patents
Pappolla's latest patents include innovative methods for utilizing indole-3-propionic acids and their salts and esters. His research indicates that these compounds can prevent the cytotoxic effects of amyloid beta protein on cells. Furthermore, he has developed methods for treating fibrillogenic diseases by administering effective amounts of indole-3-propionic acid. His work also highlights the potential of these compounds in reducing oxidation in biological samples and treating conditions where free radicals and oxidative stress are involved. Another significant patent focuses on a method for delaying the onset of Alzheimer's disease and other amyloidosis-related disorders through the use of melatonin. This method aims to reduce, inhibit, or reverse the formation of amyloid fibrils and deposits.
Career Highlights
Throughout his career, Pappolla has worked with various organizations, including the South Alabama Medical Science Foundation. His research has been instrumental in advancing the understanding of amyloidosis and its related diseases. His innovative approaches have garnered attention in the medical community, showcasing his dedication to improving patient outcomes.
Collaborations
Pappolla has collaborated with esteemed colleagues such as Blas Frangione and Jorge Ghiso. These partnerships have further enriched his research and contributed to the development of his patents.
Conclusion
Miguel A Pappolla's contributions to medical science through his patents and research are noteworthy. His innovative methods for treating amyloidosis-related diseases and oxidative stress conditions hold promise for future advancements in healthcare.