Michael McDonald

Title: Michael McDonald: Innovator in Genetic Constructs and Immunotherapy

Introduction

Michael McDonald is a notable inventor based in Guildford, GB. He has made significant contributions to the fields of genetic engineering and immunotherapy. With a total of 2 patents, his work reflects a commitment to advancing medical science and therapeutic methods.

Latest Patents

One of McDonald's latest patents is a genetic construct that comprises a promoter operably linked to a first coding sequence, which encodes tyrosine hydroxylase (TH), and a second coding sequence, which encodes GTP cyclohydrolase 1 (GCH1). In this construct, the second coding sequence is positioned 3' to the first coding sequence, and both sequences are part of a single operon. Notably, this genetic construct does not encode aromatic amino acid decarboxylase (AADC). Another significant patent is an immunotherapeutic method that provides a way to monitor the efficacy of an immunotherapy in a mammalian subject. This method involves administering a viral vector containing a polynucleotide encoding an antigen, which is capable of transducing cells in the subject to express the antigen.

Career Highlights

Throughout his career, McDonald has worked with various companies, including Healing Genes LLC and Panacea Venture Healthcare Fund I, LP. His experience in these organizations has allowed him to develop and refine his innovative ideas in the medical field.

Collaborations

Michael McDonald has collaborated with notable individuals such as Richard Harrop and William Shingler. These partnerships have contributed to the advancement of his research and inventions.

Conclusion

Michael McDonald stands out as an influential inventor in the realms of genetic constructs and immunotherapy. His patents and collaborations reflect his dedication to improving health outcomes through innovative solutions.