Michael J Griffith

Title: Michael J Griffith: Innovator in Biopharmaceutical Purification

Introduction

Michael J Griffith is a notable inventor based in Claremont, CA (US). He has made significant contributions to the field of biopharmaceuticals, particularly in the purification processes of critical therapeutic proteins. With a total of 3 patents to his name, Griffith's work has had a substantial impact on medical treatments.

Latest Patents

Griffith's latest patents include an ultrapurification process for Factor VIII and a viral-safe purified human thrombin. The ultrapurification process for Factor VIII:C involves a series of steps that include contacting an immobilized antibody with Factor VIII:C, desorbing it, and eluting the purified product. This innovative method enhances the quality and safety of Factor VIII, which is essential for hemophilia treatment. His second patent describes a therapeutic-grade thrombin that is free of lipid envelope viruses, ensuring its safety for human administration. This thrombin has a specific activity range of about 2200 to 3200 NIH units per milligram of protein, making it suitable for commercial-scale production.

Career Highlights

Griffith is currently associated with Baxter International Inc., a leading company in the biopharmaceutical industry. His work at Baxter has allowed him to focus on developing advanced purification techniques that are crucial for producing safe and effective therapeutic products.

Collaborations

Throughout his career, Griffith has collaborated with esteemed colleagues such as Joyce E Lawrence and Gerard G Neslund. These partnerships have fostered innovation and have contributed to the successful development of his patented technologies.

Conclusion

Michael J Griffith's contributions to biopharmaceutical purification processes exemplify the importance of innovation in healthcare. His patents not only enhance the safety and efficacy of critical therapeutic proteins but also reflect his commitment to advancing medical science.