Michael G Klein

Title: Michael G. Klein: Innovator in Pheromone Research

Introduction

Michael G. Klein is a notable inventor based in Wooster, Ohio. He has made significant contributions to the field of pheromone research, particularly in understanding the chemical signals used by insects for communication. His work has implications for pest management and ecological studies.

Latest Patents

Klein holds a patent for a sex pheromone produced by the female Japanese beetle, Popilla japonica. The patent details the specificity of the compound (Z)-5-(1-decenyl)dihydro-2(3H)-furanone, which was isolated from virgin female Japanese beetles. This compound was shown to attract male beetles in field bioassays. Interestingly, the synthesized racemic mixture of this compound did not attract male Japanese beetles. The research also involved synthesizing the Z- and E-isomers and the saturated analog of both enantiomers stereospecifically. The pure synthetic (R,Z)-5-(1-decenyl)dihydro-2(3H)-furanone was found to be competitive with live females and the pheromone isolated from them in attracting males. However, the male response was significantly inhibited by small amounts of the (S,Z)-isomer.

Career Highlights

Klein's career is marked by his innovative research and contributions to the understanding of insect pheromones. His work has provided valuable insights into the chemical ecology of the Japanese beetle, which is important for developing effective pest control strategies.

Collaborations

Throughout his career, Klein has collaborated with notable colleagues, including James H. Tumlinson III and Robert E. Doolittle. These collaborations have enhanced the depth and impact of his research in the field.

Conclusion

Michael G. Klein's work in pheromone research exemplifies the intersection of innovation and ecological understanding. His contributions continue to influence the field and offer potential solutions for pest management.