Location History:
- Maple Glen, PA (US) (1978)
- Somerset, NJ (US) (1978)
Company Filing History:
Years Active: 1978
Title: Michael C Vander Zwan: Innovator in Pharmaceutical Chemistry
Introduction
Michael C Vander Zwan is a notable inventor based in Maple Glen, PA (US). He has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of compounds with therapeutic applications. With a total of 2 patents, Vander Zwan's work has had a meaningful impact on the industry.
Latest Patents
Vander Zwan's latest patents include a process for the preparation of 9-(2,6-dihalobenzyl)adenines. This innovative method involves allowing 2,6-dihalobenzyl halides to react with a salt of adenine in a solid-liquid or liquid-liquid two-phase system, utilizing an onium salt phase transfer catalyst. The resulting compounds exhibit anticoccidial activity, proving useful in controlling cecal and/or intestinal coccidiosis in animals, particularly poultry, when administered in minor quantities alongside animal sustenance. Another significant patent is for the preparation of 4,6-diamino-5-arylazopyrimidines and adenine compounds. This process involves preparing 4,6-diamino-5-arylazopyrimidine from an arylazomalononitrile in the presence of ammonium chloride and formamide. The compound can be further hydrogenated to yield 4,5,6-triaminopyrimidine, which can produce adenine when hydrogenation occurs in the presence of formic acid or its derivative.
Career Highlights
Vander Zwan is associated with Merck & Co., Inc., a leading global healthcare company. His work at Merck has allowed him to focus on innovative solutions in drug development and contribute to advancements in pharmaceutical sciences.
Collaborations
One of his notable collaborators is Donald F Reinhold, with whom he has worked on various projects in the field of pharmaceutical chemistry.
Conclusion
Michael C Vander Zwan's contributions to pharmaceutical chemistry through his patents and work at Merck & Co., Inc. highlight his role as an influential inventor in the industry. His innovative processes for preparing important compounds demonstrate his commitment to advancing healthcare solutions.
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