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Years Active: 2023-2024
Title: Megan McCain: Innovator in Cardiac Regeneration
Introduction
Megan McCain is a prominent inventor based in Los Angeles, CA, known for her groundbreaking work in cardiac regeneration. She holds 2 patents that focus on innovative solutions for studying heart repair using zebrafish as a model organism. Her research has significant implications for understanding heart regeneration and developing new therapeutic strategies.
Latest Patents
One of her latest patents is a fluidic device designed for long-term explant culture and imaging of adult zebrafish hearts. Zebrafish are recognized for their unique regenerative abilities, making them an ideal model for cardiac research. However, studying the regeneration process in live adult zebrafish has been challenging due to their opaque nature and the rapid decline in morphology and physiology of explanted hearts in conventional culture conditions. To address these challenges, McCain's fluidic device allows for constant media perfusion and is compatible with live imaging. This innovation enables researchers to maintain the morphology and calcium activity of cultured hearts, providing unprecedented visual access to the multi-day process of heart regeneration.
Career Highlights
Megan McCain has made significant contributions to the field of cardiac research through her work at esteemed institutions such as the University of Southern California and Children's Hospital Los Angeles. Her research has not only advanced scientific understanding but also opened new avenues for potential therapies in cardiac repair.
Collaborations
Throughout her career, McCain has collaborated with talented individuals, including Joycelyn Yip and Ching-Ling Lien. These collaborations have enriched her research and contributed to the success of her innovative projects.
Conclusion
Megan McCain's contributions to cardiac regeneration research through her innovative patents and collaborations highlight her role as a leading inventor in the field. Her work continues to inspire advancements in understanding heart repair and regeneration.