Company Filing History:
Years Active: 1990
Title: The Innovations of Maurice Haufler
Introduction
Maurice Haufler is a notable inventor based in Kerrville, TX (US). She has made significant contributions to the field of biotechnology, particularly in the development of monoclonal antibodies. Her work has implications for pest control and agricultural biotechnology.
Latest Patents
Haufler holds a patent for "Monoclonal antibodies to crystal protein of Bacillus thuringiensis." This patent describes murine hybridomas constructed by fusing spleen cells from BALB/c mice immunized with soluble crystal protein from Bacillus thuringiensis subsp. israelensis (B.t.i.) to the murine myeloma cell line SP2/0-AG14. An ELISA method for detecting antibodies specific for the crystal protein of B.t.i. was modified to produce a 100- to 1,000-fold increase in sensitivity. This method was utilized to identify hybridomas secreting monoclonal antibodies specific for the B.t.i. crystal protein. Analysis of the hybridoma culture supernatant fluid indicated the production of monoclonal IgG3 antibodies, which are specific for the 68,000 dalton protein presumed to be the insecticidal delta-endotoxin of B.t.i. Haufler's innovative work has led to advancements in the detection and application of these antibodies.
Career Highlights
Maurice Haufler has worked with the United States of America as represented by the Secretary of Agriculture. Her career has been marked by a commitment to research and development in the field of biotechnology. She has demonstrated a strong ability to innovate and contribute to scientific advancements.
Collaborations
Haufler has collaborated with notable colleagues such as Kevin B. Temeyer and John H. Pruett. These collaborations have enhanced her research and contributed to the success of her projects.
Conclusion
Maurice Haufler's contributions to the field of biotechnology through her patent on monoclonal antibodies exemplify her innovative spirit and dedication to scientific research. Her work continues to influence the agricultural sector and improve pest control methods.