Company Filing History:
Years Active: 2014-2018
Title: Matthew Schaab: Innovator in Biospecimen Integrity Assessment
Introduction
Matthew Schaab is a notable inventor based in Phoenix, AZ (US), recognized for his contributions to the field of biospecimen integrity. With a focus on innovative methods for assessing and quantifying the integrity of biological samples, Schaab has made significant strides in enhancing the reliability of biospecimen analysis.
Latest Patents
Schaab holds 2 patents, with his latest inventions focusing on methods for assessing biospecimen integrity. One of his notable patents is titled "Methods for quantifying biospecimen sample integrity using markers of oxidation." This invention addresses the challenges associated with incomplete blood plasma or serum sample freezing, particularly at temperatures of -20 °C. The patent details the spontaneous oxidation processes that occur at protein sulfur atoms, leading to S-cysteinylation and sulfoxidation of methionine. These oxidative changes result in oxidized forms of albumin and apoA-1, which serve as useful markers for evaluating biospecimen integrity. Additionally, the invention proposes custom-designed surrogate peptide probes to enhance sample integrity during collection.
Career Highlights
Matthew Schaab is affiliated with Arizona State University, where he continues to advance research in biospecimen integrity. His work is pivotal in developing reagents and methods that limit protein losses due to adsorption and oxidation in biological samples. This research is crucial for ensuring the accuracy and reliability of biospecimen analysis in various scientific fields.
Collaborations
Schaab collaborates with esteemed colleagues, including Douglas Rehder and Chad Borges, to further enhance the impact of his research. Their combined expertise contributes to the development of innovative solutions in the realm of biospecimen integrity.
Conclusion
Matthew Schaab's innovative work in biospecimen integrity assessment highlights the importance of reliable sample analysis in scientific research. His contributions through patents and collaborations continue to shape the future of biospecimen research and its applications.