Company Filing History:
Years Active: 1997
Title: Mathias Herrlein: Innovator in Fluorescent Dye-Coupled Nucleosides
Introduction
Mathias Herrlein is a notable inventor based in Frankfurt am Main, Germany. He has made significant contributions to the field of biochemistry, particularly in the development of fluorescent dye-coupled nucleosides. With a total of 3 patents to his name, Herrlein's work has the potential to advance genetic material detection techniques.
Latest Patents
Herrlein's latest patents include innovative methods for creating 3'-(2')-amino- or thiol-modified, fluorescent dye-coupled nucleosides, nucleotides, and oligonucleotides. These inventions involve the derivatization of the OH group located in the 3' and/or 2' position of nucleosides, nucleotides, or oligonucleotides to an amino or thiol group, followed by the coupling of a fluorescent dye. The resulting modified nucleosides and nucleotides can be utilized for synthesizing complementary strands in the presence of a template strand or oligonucleotides, enhancing the detection of genetic material. This method offers advantages over conventional labeling techniques, as it eliminates the need to attach the fluorescent label to the 5' end of the oligonucleotide or nucleobase during chemical synthesis.
Career Highlights
Mathias Herrlein is associated with Hoechst Aktiengesellschaft, a prominent company in the chemical and pharmaceutical industry. His work at Hoechst has allowed him to focus on innovative solutions in the field of nucleic acid research.
Collaborations
Throughout his career, Herrlein has collaborated with esteemed colleagues such as Joachim Engels and Renate Konrad. These partnerships have contributed to the advancement of his research and the successful development of his patented technologies.
Conclusion
Mathias Herrlein's contributions to the field of fluorescent dye-coupled nucleosides represent a significant advancement in genetic material detection. His innovative patents and collaborations highlight his role as a leading inventor in biochemistry.