Masatoshi Tohata

Title: Masatoshi Tohata: Innovator in Protease Development

Introduction

Masatoshi Tohata is a prominent inventor based in Haga-gun, Japan. He has made significant contributions to the field of biochemistry, particularly in the development of mutant proteases and detergents for corneum-derived stains. With a total of 10 patents to his name, Tohata's work has had a considerable impact on both scientific research and practical applications.

Latest Patents

Tohata's latest patents include a mutant protease designed to exhibit improved stability under acidic conditions. This mutant protease consists of an amino acid sequence that has at least 90% identity to a specified sequence, with a key substitution at position 303. Additionally, he has developed a detergent specifically targeting corneum-derived stains, which utilizes a M23A subfamily protease as its active ingredient. The method for evaluating the enzyme's ability to degrade these stains involves assessing its activity on reference and substrate peptides, providing a robust framework for enzyme evaluation.

Career Highlights

Throughout his career, Masatoshi Tohata has worked with notable organizations such as Kao Corporation and the Nara Institute of Science and Technology. His experience in these institutions has allowed him to refine his expertise in protease research and development, leading to innovative solutions in the field.

Collaborations

Tohata has collaborated with esteemed colleagues, including Keiji Endo and Kazuhisa Sawada. These partnerships have fostered a collaborative environment that has enhanced the quality and impact of his research.

Conclusion

Masatoshi Tohata's contributions to the field of protease development and his innovative approaches to tackling corneum-derived stains highlight his significance as an inventor. His work continues to influence both academic research and practical applications in biochemistry.