Mary L Mangano

Title: Mary L Mangano: A Pioneer in Genetically Transformed Maize Research

Introduction

Mary L Mangano, an accomplished inventor based in Westerly, Rhode Island, has made significant contributions to the field of plant biotechnology. With a remarkable portfolio consisting of five patents, her work primarily focuses on the genetic transformation of monocot plants, particularly maize.

Latest Patents

Mary's most recent patents include innovative methods and compositions for the production of stably transformed, fertile monocot plants and the cells derived from them. One notable invention relates to a reproducible system for generating stable, genetically transformed maize cells. This system includes methods for selecting transformed cells using a bar gene introduced via microprojectile bombardment into embryogenic maize cells. Following exposure to the herbicide bialaphos, the transformation becomes a pivotal aspect of her work. Mary's creations also encompass methods for achieving stable transformation through tissue culture techniques, media, and regeneration of fertile plants from these transformed cells.

Additionally, her inventions incorporate strategies for producing genetically modified Zea mays plants that exhibit resistance to phosphinothricin and insect resistance through the expression of a Bacillus thuringiensis toxin gene. These methods showcase her expertise in plant breeding and the regeneration of fertile transgenic plants.

Career Highlights

Mary L Mangano is currently associated with Dekalb Genetics Corporation, where she has honed her skills and expanded her research capabilities. Her contributions to the field of plant genetics exemplify her commitment to advancing agricultural technology and sustainability. Through her innovations, she aims to create more resilient crop varieties that can withstand environmental challenges.

Collaborations

Mary has collaborated with notable colleagues, including Thomas R Adams and Sheryl A Chambers. These collaborations have fostered a productive environment for innovation and have enhanced the impact of her work within the scientific community.

Conclusion

Mary L Mangano's dedication to her craft and her innovative approaches have positioned her as a key figure in the realm of genetically transformed maize research. Her five patents reflect her substantial contributions and the potential for further advancements in agricultural biotechnology. As she continues to explore new horizons in her field, her work will undoubtedly influence future generations of inventors and researchers.