Company Filing History:
2 out of 3,446 
1 out of 2,202 
1 out of 1,217 
Years Active: 1996-2004
Title: The Innovative Contributions of Mary E. Hawkins
Introduction
Mary E. Hawkins is a distinguished inventor based in Potomac, MD (US), known for her significant contributions to the field of biochemistry and molecular biology. With a total of four patents to her name, Hawkins has made remarkable advancements in the development of fluorescent nucleotide analogs and their applications in nucleic acid detection.
Latest Patents
Hawkins' latest patents include innovative inventions such as pteridine nucleotide analogs. This invention provides pteridine nucleotides of formula (I) that are highly fluorescent and can be utilized in the chemical synthesis of fluorescent oligonucleotides. Additionally, the invention offers fluorescent oligonucleotides comprising one or more pteridine nucleotides. The pteridine nucleotide triphosphates developed in this patent may serve as constituent monomers in DNA amplification procedures. These nucleotides are noted for their stability and higher quantum yields compared to structurally similar pteridine nucleotides.
Another significant patent by Hawkins focuses on fluorescent nucleotide analog hairpin formation for the detection of nucleic acid hybridization. This invention outlines methods and compositions for detecting nucleic acid interactions with other nucleic acids or proteins. The methods utilize a nucleic acid, such as an oligonucleotide, that contains one or more fluorescent nucleotide analogues. The fluorescence of these analogues is quenched when incorporated into the oligonucleotide. However