Location History:
- San Diego, CA (US) (1994 - 1997)
- Schiedam, NL (1996 - 1998)
Company Filing History:
Years Active: 1994-1998
Title: Marti F Bierhuizen: Innovator in Human Glycosylation Research
Introduction
Marti F Bierhuizen is a notable inventor based in San Diego, California. He has made significant contributions to the field of glycosylation, particularly through his research on human beta-1,6-N-acetylglucosaminyltransferase (IGnT). With a total of seven patents to his name, Bierhuizen's work has implications for both basic science and therapeutic applications.
Latest Patents
Bierhuizen's latest patents include groundbreaking inventions related to the expression of the developmental I antigen by a cloned human cDNA. His inventions provide isolated nucleic acid molecules encoding both soluble and membrane-bound forms of human IGnT. These patents also encompass vectors containing the isolated nucleic acid molecule, as well as recombinant host cells transformed with these vectors. Furthermore, he has developed methods for preparing and purifying both soluble and membrane-bound forms of human IGnT. His work includes the creation of antisense oligonucleotides, antibodies directed to human IGnT, and pharmaceutical compositions related to this enzyme. Additionally, he has outlined methods for regulating the expression of human IGnT and detecting linear polylactosaminoglycans expressing I antigenic determinants on cell surfaces.
Career Highlights
Throughout his career, Bierhuizen has worked with esteemed organizations such as the La Jolla Cancer Research Foundation and the La Jolla Cancer Research Center. His research has been pivotal in advancing our understanding of glycosylation and its role in human health.
Collaborations
Bierhuizen has collaborated with notable scientists in his field, including Minoru Fukuda, who has contributed to the research on glycosylation and its implications in cancer biology.
Conclusion
Marti F Bierhuizen's innovative work in the field of glycosylation has led to significant advancements in our understanding of human biology and potential therapeutic applications. His contributions continue to influence research and development in this critical area of science.