Location History:
- Nutley, NJ (US) (2000)
- Fairfield, NJ (US) (2011)
Company Filing History:
Years Active: 2000-2011
Title: Martha V Ray: Innovator in Peptide Expression Technologies
Introduction
Martha V Ray is a prominent inventor based in Fairfield, NJ (US), known for her significant contributions to the field of biotechnology. With a total of two patents to her name, she has made remarkable advancements in the direct expression of peptides into culture media.
Latest Patents
Martha's latest patents focus on innovative expression systems that enable the direct expression of peptide products into the culture media where genetically engineered host cells are cultivated. These systems achieve high yields through the use of novel vectors, a carefully selected range of host cells, and fermentation processes that involve meticulous control of cell growth rates. Additionally, the use of an inducer during the growth phase enhances the efficiency of peptide production. The special vectors developed by Martha include control regions with multiple promoters that are operably linked to coding regions encoding a signal peptide, which is positioned upstream from the coding region for the peptide of interest. Furthermore, multiple transcription cassettes are employed to maximize yield, and the production of amidated peptides using these expression systems is also disclosed.
Career Highlights
Martha V Ray has established herself as a key figure in her field, working at Unigene Laboratories Inc., where she continues to innovate and develop new technologies. Her work has not only advanced scientific understanding but has also contributed to practical applications in biotechnology.
Collaborations
Martha collaborates with esteemed colleagues, including Nozer M Mehta and Angelo P Consalvo, who share her commitment to advancing peptide expression technologies.
Conclusion
Martha V Ray's contributions to the field of biotechnology, particularly in peptide expression systems, highlight her role as an influential inventor. Her innovative approaches and collaborative efforts continue to drive advancements in this important area of research.