Company Filing History:
Years Active: 2025
Title: Mark Richard Berglund: Innovator in Peptide Synthesis
Introduction
Mark Richard Berglund is a notable inventor based in Zionsville, Indiana. He has made significant contributions to the field of peptide synthesis, holding 2 patents that showcase his innovative approaches to manufacturing peptides.
Latest Patents
Berglund's latest patents include a "Three resin reactors in series peptide synthesizer," which is a Solid Phase Peptide Synthesis (SPPS) device and method. This invention involves a system comprising at least two reactors, each containing SPPS resin, positioned in series. A de-protecting agent is added to the first reactor and then transferred to the subsequent reactors, effectively de-protecting the protected N-group. The process also includes the addition of wash solvent and amino acid activated ester solutions in a series manner, which optimizes the coupling of amino acids to the de-protected N-group while reducing the overall solvent required. Additionally, online LCMS is utilized to monitor the reactions occurring within the solid phase resin particles.
Another significant patent by Berglund focuses on "Processes and intermediates for preparing tirzepatide." This invention provides new intermediates and processes that are useful in the manufacture of tirzepatide or its pharmaceutically acceptable salts.
Career Highlights
Mark Richard Berglund is currently employed at Eli Lilly and Company, where he continues to advance his research and development efforts in the pharmaceutical industry. His work has contributed to the enhancement of peptide synthesis techniques, which are crucial for drug development.
Collaborations
Berglund has collaborated with notable coworkers, including Michael E Kopach and Rachel Nicole Richey, who have also contributed to advancements in the field of peptide synthesis.
Conclusion
Mark Richard Berglund is a distinguished inventor whose work in peptide synthesis has led to innovative solutions in the pharmaceutical industry. His patents reflect a commitment to improving manufacturing processes and enhancing the efficiency of peptide production.