Location History:
- Boston, MA (US) (1993 - 1996)
- Needham, MA (US) (2004)
Company Filing History:
3 out of 1,373 
1 out of 13 Years Active: 1993-2004
Title: Innovations and Contributions of Mark A. Goldberg
Introduction
Mark A. Goldberg is a notable inventor based in Boston, MA, with a significant contribution to the field of biotechnology. He holds four patents that reflect his innovative approach to enhancing cellular functions and addressing medical challenges. His work primarily focuses on gene expression and vascularization, which are critical areas in medical research and treatment.
Latest Patents
One of Goldberg's latest patents is titled "Hypoxia responsive transcription enhancer element from yeast." This invention is directed towards DNA elements that enhance cellular gene expression in response to anaerobic growth or the presence of specific inducing agents. The enhancer element can be incorporated into expression vectors to increase the production of recombinant proteins. Another significant patent is "Induction of vascular endothelial growth factor (VEGF) by transition." This patent discusses how transition metal ions can enhance the body's ability to increase vascularization, particularly for revascularizing damaged tissues. The invention outlines methods for treating hypoxic tissue damage by administering a composition that includes a transition metal ion, formulated in a way that is effective and non-toxic.
Career Highlights
Throughout his career, Mark A. Goldberg has worked with prestigious institutions such as Brigham and Women's Hospital, Inc. and Beth Israel Hospital Association. His experience in these organizations has allowed him to collaborate with leading professionals in the field and contribute to groundbreaking research.
Collaborations
Goldberg has collaborated with notable colleagues, including Andrew P. Levy and Carlo Brugnara. These partnerships have further enriched his research and innovation efforts.
Conclusion
Mark A. Goldberg's contributions to biotechnology through his patents and collaborations highlight his role as an influential inventor. His work continues to impact the medical field, particularly in enhancing gene expression and vascularization.