Company Filing History:
Years Active: 2015
Title: Marilyne Blain - Innovating Muscle Gene Expression
Introduction
Marilyne Blain is a notable inventor based in Lorraine, CA. With her innovative contributions, she has made significant strides within the field of gene therapy. Her work emphasizes the enhancement of gene expression in muscle fibers, showcasing her dedication to advancing medical and scientific knowledge.
Latest Patents
Marilyne is the holder of a patent that focuses on constructs for the enhancement of gene expression in muscle. Her patent outlines how efficient and muscle-specific gene expression can be achieved through constructs containing two or more copies of USE and/or ∆USE fused to the minimal promoter of the TnISlow gene. USE is a small upstream enhancer that significantly confers slow-twitch muscle fiber specificity. The ∆USE variation, resulting from a specific deletion at the 5' end of USE, allows for expression in both slow- and fast-twitch muscle fibers. The compact nature of these constructs, all under 600-bp, renders them particularly advantageous for gene therapy applications.
Career Highlights
Marilyne currently serves in the esteemed National Research Council of Canada, where she applies her expertise in genetic research and development. Her focused research aims to utilize her patented constructs to further the understanding of muscle gene expression and contribute to therapeutic applications.
Collaborations
Throughout her career, Marilyne has collaborated with key figures in her field, including her coworkers Bernard Massie and Renald Gilbert. These partnerships have enabled her to enhance her research efforts and foster a collaborative environment that encourages innovation and discovery.
Conclusion
Marilyne Blain's contributions to the field of gene therapy through her patented work not only reflect her individual talents and dedication but also demonstrate the potential for future advancements in muscle gene expression. Her innovations are paving the way for targeted therapies that may dramatically transform medical treatments in the years to come.