Marie H Wroble

Title: Marie H Wroble: Innovator in Protein Engineering

Introduction

Marie H Wroble is a distinguished inventor based in Mt. Airy, MD (US). She has made significant contributions to the field of protein engineering, particularly in the development of binding proteins and purification processes. With a total of 2 patents, her work has advanced the understanding and application of immunoglobulin G (IgG) binding proteins.

Latest Patents

Wroble's latest patents include "Immobilized protein G variants and the use thereof" and "Process for manufacture of L-asparaginase from Erwinia chrysanthemi." The first patent focuses on immobilized IgG binding proteins that enhance affinity chromatography and facilitate the separation of IgG subclasses. This innovation involves cysteine-containing IgG binding proteins that exhibit high binding capacity for both human IgG and mouse monoclonal IgG. The second patent outlines a method for recovering and purifying L-asparaginase from Erwinia chrysanthemi, detailing a process that includes the preparation of cellular acetone powder extract followed by purification steps.

Career Highlights

Throughout her career, Wroble has worked with notable organizations, including Genex Corporation and the United States of America as represented by the Department of Health. Her expertise in protein engineering has positioned her as a key figure in her field.

Collaborations

Wroble has collaborated with esteemed colleagues such as Stephen R Fahnestock and Timothy Lee, contributing to various projects that have furthered advancements in protein research.

Conclusion

Marie H Wroble's innovative work in protein engineering and her contributions to the field through her patents highlight her as a significant inventor. Her advancements in binding proteins and purification processes continue to impact the scientific community.