Company Filing History:
Years Active: 1999-2007
Title: The Innovative Journey of Marianne Langston
Introduction
Marianne Langston is a distinguished inventor based in Cambridge, GB. She has made significant contributions to the field of chemistry, particularly in the development of pharmaceutical processes. With a total of 3 patents to her name, her work has had a notable impact on the industry.
Latest Patents
One of her latest patents is focused on the manufacture of single isomer methylphenidate. This invention pertains to a process for obtaining a single enantiomer, either d or l, of threo-methylphenidate. The process involves the resolution of a mixture of the enantiomers, racemisation of the unwanted enantiomer, and separation of the erythro stereoisomers. This innovative approach allows for the efficient production of the desired enantiomer.
Another significant patent by Langston is related to the racemisation process for the manufacture of levobupivacaine and related piperidinecarboxanilide anaesthetic agents. In this process, an optically-enriched piperidine-2-carboxanilide compound is racemized by heating it in an aqueous medium. The inclusion of an organic co-solvent is crucial if the compound is N-alkylated. This method is particularly valuable when used in conjunction with a resolution process for the manufacture of levobupivacaine.
Career Highlights
Throughout her career, Marianne Langston has worked with notable companies such as Darwin Discovery Limited and Celltech Pharma Europe Limited. Her expertise in pharmaceutical chemistry has allowed her to contribute to various innovative projects and advancements in the field.
Collaborations
Langston has collaborated with esteemed colleagues, including Benjamin Mark Skead and Ulrich Conrad Dyer. These partnerships have further enriched her work and expanded the scope of her inventions.
Conclusion
Marianne Langston's contributions to the field of chemistry and her innovative patents demonstrate her commitment to advancing pharmaceutical processes. Her work continues to influence the industry and inspire future innovations.
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