Company Filing History:
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1 out of 832,761 Years Active: 1993-1997
Title: Innovations of Marianne Borowski
Introduction
Marianne Borowski is a notable inventor based in Boston, MA. She has made significant contributions to the field of biochemistry, particularly in the development of oligosaccharide conjugates. With a total of two patents to her name, her work has the potential to enhance drug delivery systems and improve biological properties of proteins.
Latest Patents
Her latest patents focus on the production of oligosaccharide oxazolines and oligosaccharide conjugates. One of her inventions relates to a method of producing peracetyloxazolines from peracetyl saccharides. This method involves reacting a peracetyl saccharide with a specific reagent combination to directly produce the peracetyl oxazoline. The process is designed for the activation of oligosaccharides, particularly those containing a reducing GlcNAc terminus. By forming an oxazolide at the terminal GlcNAc, the oligosaccharide can be coupled with a bifunctional spacer, resulting in an oligosaccharide-spacer conjugate. This conjugate can then be attached to proteins, such as granulocyte colony-stimulating factor or gamma-interferon, leading to the creation of neoglycoprotein conjugates. These innovations may significantly improve the serum lifetime and efficiency of drug delivery to target organs or cells.
Career Highlights
Throughout her career, Marianne has worked with prominent organizations, including Genzyme Corporation. Her expertise in biochemistry and innovative approaches have positioned her as a valuable contributor to her field.
Collaborations
Marianne has collaborated with notable professionals, including Marcelo Colon and Jeffrey T. Davis. Their combined efforts have further advanced the research and development of her innovative projects.
Conclusion
Marianne Borowski's contributions to the field of biochemistry through her patents and collaborations highlight her role as a pioneering inventor. Her work continues to influence advancements in drug delivery and protein engineering.