Company Filing History:
Years Active: 1998-2000
Title: Innovations in Genetic Research: The Contributions of Marga Belle White
Introduction
Marga Belle White, an accomplished inventor based in Frederick, MD, has made significant strides in the field of genetic research. With a total of four patents to his name, Marga has focused primarily on identifying cancer susceptibility mutations in the BRCA1 and BRCA2 genes. His groundbreaking work not only sheds light on genetic predispositions to cancer but also enhances methods for mutation detection, aiding in the advancement of personalized medicine.
Latest Patents
Marga's most recent patents detail the discovery of new mutations in the BRCA1 gene, which are located at specific nucleotide positions including 421-2, 815, 903, 926, 1506, 2034, 2428, 3888, 3904, 4164, 4643, 5053, 5150, 5210, and 5396+40. His innovative process for identifying sequence variations in the BRCA1 polynucleotide sequence includes allele-specific sequence-based assays of known variations, facilitating accurate detection of mutations in BRCA1 gene samples.
Similarly, his work on the BRCA2 gene has also led to the identification of new mutations at nucleotide positions 2192, 3772, 5193, 5374, 6495, and 6909. This patent outlines a process for detecting variations in the BRCA2 polynucleotide sequence using the same advanced methods, thus broadening the scope for accurate mutation detection in clinical samples.
Career Highlights
Throughout his career, Marga has worked with notable companies in the biotechnology sector, including Oncormed, Inc. and Gene Logic, Inc. His focus on genetic research and cancer susceptibility has positioned him as a prominent figure in the field, driving forward advancements that have the potential to save lives by enabling earlier detection of hereditary cancers.
Collaborations
Collaboration has been a significant aspect of Marga's career. He has worked alongside esteemed colleagues such as Lisa K Sadzewicz and Sheri J Olson. Their combined expertise has contributed to the research and development of innovative solutions for genetic mutation detection, fostering a team environment that encourages scientific inquiry and innovation.
Conclusion
Marga Belle White stands out as an influential inventor in the realm of genetics, particularly in understanding cancer susceptibility through BRCA1 and BRCA2 mutations. His innovative patents reflect a dedication to enhancing detection methods that can significantly impact patient outcomes. As he continues to forge ahead in his research, Marga’s work exemplifies the critical role inventors play in advancing medical science and improving public health.