Location History:
- Gurabo, PR (US) (1993)
- Gurabo, PR (1997)
Company Filing History:
1 out of 2 
1 out of 832,761 Years Active: 1993-1997
Title: Innovations by Inventor Marcelo Colon
Introduction
Marcelo Colon is an accomplished inventor based in Gurabo, Puerto Rico. He has made significant contributions to the field of oligosaccharide chemistry, holding two patents that showcase his innovative methods and applications.
Latest Patents
His latest patents focus on "Oligosaccharide oxazolines, oligosaccharide conjugates and methods of." This invention relates to a method of producing peracetyloxazolines from peracetyl saccharides. The method involves reacting the starting material, a peracetyl saccharide, with a reagent combination to directly produce the peracetyl oxazoline. This method may be used for the activation of oligosaccharides, wherein an oligosaccharide containing a reducing GlcNAc terminus is activated by the formation of an oxazolide at the terminal GlcNAc. It is then coupled with a bifunctional spacer to provide an oligosaccharide-spacer conjugate. The activated oligosaccharide-spacer conjugate is subsequently coupled to a protein, such as granulocyte colony-stimulating factor or gamma-interferon, resulting in a neoglycoprotein conjugate. This invention provides a method for forming neoglycoprotein conjugates that may improve the biological and physiochemical properties of the protein. For example, it may enhance serum lifetime or the efficiency of drug delivery of the peptide to a target organ or cell.
Career Highlights
Throughout his career, Marcelo Colon has worked with notable organizations, including Genzyme Corporation. His work has significantly impacted the field of biochemistry and drug delivery systems.
Collaborations
Some of his coworkers include Jeffrey T. Davis and James R. Rasmussen, who have contributed to his innovative projects and research endeavors.
Conclusion
Marcelo Colon's contributions to oligosaccharide chemistry and his innovative patents demonstrate his commitment to advancing scientific knowledge and improving drug delivery systems. His work continues to influence the field and inspire future innovations.