Company Filing History:
Years Active: 1994
Title: Manrico Bernardini: Innovator in Biocatalytic Processes
Introduction
Manrico Bernardini is a notable inventor based in Rome, Italy. He has made significant contributions to the field of biocatalysis, particularly in the production of L-(-)-carnitine. His innovative work has implications for various applications in pharmaceuticals and biotechnology.
Latest Patents
Manrico Bernardini holds a patent for a biocatalytic process that enables the production of L-(-)-carnitine. This process involves the stereospecific hydration of crotonobetaine through the action of an enzyme produced by four new strains of Proteus mirabilis (NRRL B-18480, NRRL B-18481, NRRL B-18482, and NRRL B-18483). The biotransformation occurs in media containing 10 to 12% (w/v) crotonobetaine inner salt. This patent showcases his expertise in enzymatic processes and their applications in producing valuable compounds.
Career Highlights
Throughout his career, Manrico Bernardini has been associated with Sigma-Tau Industrie Farmaceutiche Riunite S.p.a., where he has contributed to various research and development projects. His work has focused on enhancing biocatalytic processes, which are crucial for sustainable and efficient production methods in the pharmaceutical industry.
Collaborations
Manrico has collaborated with esteemed colleagues such as Stuart Shapiro and Charles J. Sih. These partnerships have fostered innovation and have been instrumental in advancing research in biocatalysis and related fields.
Conclusion
Manrico Bernardini's contributions to the field of biocatalysis, particularly through his patented process for producing L-(-)-carnitine, highlight his role as an influential inventor. His work continues to impact the pharmaceutical industry positively.