Manman Zhang

Title: Manman Zhang: Innovator in Immunomodulatory Hydrogels

Introduction

Manman Zhang is a prominent inventor based in Tianjin, China. He has made significant contributions to the field of biomedical engineering, particularly in the development of innovative hydrogels. His work focuses on creating materials that can modulate immune responses, which has important implications for medical treatments.

Latest Patents

Manman Zhang holds a patent for an "Immunomodulatory hydrogel and preparation method thereof." This innovative hydrogel is prepared using methoxy polyethylene glycol amine (mPEG-NH) as an initiator. The mPEG-NH reacts with L-tyrosine-N-carboxyanhydrides (L-Tyr-NCAs) to form a methoxy polyethylene glycol-poly L-tyrosine (PETyr) block copolymer. The PETyr is then reacted with tyrosinase to create an oxidized methoxy polyethylene glycol-poly L-tyrosine copolymer (PETO). By co-dissolving the PETO with octyl itaconate nanomicelles (ITA8) in a disperse medium, an itaconic acid-loaded immunomodulatory hydrogel (PETO-ITA8) is obtained. This patent highlights his innovative approach to enhancing immune responses through advanced materials.

Career Highlights

Manman Zhang is affiliated with the Institute of Radiation Medicine, Chinese Academy of Medical Sciences, and Peking Union Medical College. His work in these prestigious institutions has allowed him to collaborate with leading experts in the field. His research has garnered attention for its potential applications in medical therapies and treatments.

Collaborations

Manman Zhang has worked alongside notable colleagues, including Huijuan Song and Qiang Liu. Their collaborative efforts have contributed to advancements in the field of immunomodulatory materials.

Conclusion

Manman Zhang is a key figure in the development of immunomodulatory hydrogels, with a focus on innovative biomedical applications. His contributions to the field are paving the way for new therapeutic strategies.