Makoto Asamoto

Title: The Innovative Contributions of Makoto Asamoto

Introduction

Makoto Asamoto is a prominent inventor based in Nagoya, Japan. He has made significant contributions to the field of medical research, particularly in the development of animal models for studying diseases. His work focuses on creating innovative solutions that can aid in understanding complex health issues.

Latest Patents

Asamoto holds a patent for a model rat with the onset of prostatic cancer. This invention aims to provide a rat model that can develop prostate cancer, including invasive forms of the disease, and can be bred for generations stably. The patent describes a method of ligating an SV40 large T antigen gene onto the downstream of the rat probasin gene promoter. The resulting PBSVT transgene is introduced into a fertilized egg of a Sprague-Dawley rat. After the introduction, the fertilized egg is transplanted into a recipient rat. A transgenic rat obtained from the recipient rat is then mated with a wild-type Sprague-Dawley rat. The transgenic offspring rats can be bred for generations thereafter, and transgenic rats developing prostate cancer are selected through histopathological observation of the prostate. This innovative approach provides a valuable tool for cancer research.

Career Highlights

Makoto Asamoto is affiliated with the Japan Science and Technology Agency, where he continues to advance his research. His work has garnered attention for its potential impact on understanding prostate cancer and developing new treatment strategies. Asamoto's dedication to scientific innovation is evident in his research and patent contributions.

Collaborations

Asamoto collaborates with notable colleagues, including Tomoyuki Shirai and Satoru Takahashi. Their combined expertise enhances the research efforts at the Japan Science and Technology Agency, fostering an environment of innovation and discovery.

Conclusion

Makoto Asamoto's contributions to medical research, particularly through his patent for a rat model of prostate cancer, highlight his role as an influential inventor. His work not only advances scientific understanding but also paves the way for future innovations in cancer research.