Cambridge, MA, United States of America

Maja Janas

USPTO Granted Patents = 5 

Average Co-Inventor Count = 12.2

ph-index = 2

Forward Citations = 19(Granted Patents)


Company Filing History:


Years Active: 2021-2025

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5 patents (USPTO):Explore Patents

Title: Maja Janas: Innovator in RNA Therapeutics

Introduction

Maja Janas is a prominent inventor based in Cambridge, MA (US), known for her significant contributions to the field of RNA therapeutics. With a total of five patents to her name, she has made remarkable strides in developing innovative solutions for gene expression inhibition.

Latest Patents

One of her latest patents focuses on modified RNA agents with reduced off-target effects. This invention relates to a double-stranded RNA (dsRNA) agent capable of inhibiting the expression of a target gene. The antisense strand of the dsRNA molecule comprises at least one thermally destabilizing nucleotide occurring at a seed region. Additionally, the dsRNA includes at least four 2'-fluoro modifications, and the sense strand of the dsRNA molecule comprises a ligand, specifically an ASGPR ligand. Other aspects of this invention involve pharmaceutical compositions that include these dsRNA molecules, which are suitable for therapeutic use. The methods outlined in her patent aim to inhibit the expression of target genes, providing potential treatments for various disease conditions.

Career Highlights

Maja Janas is currently employed at Alnylam Pharmaceuticals, Inc., where she continues to advance her research in RNA therapeutics. Her work has positioned her as a key figure in the development of innovative treatments that leverage RNA technology.

Collaborations

Maja collaborates with esteemed colleagues, including Mark K Schlegel and Vasant R Jadhav, contributing to a dynamic research environment that fosters innovation and discovery.

Conclusion

Maja Janas exemplifies the spirit of innovation in the field of RNA therapeutics, with her groundbreaking patents paving the way for new treatment options. Her contributions are vital to the ongoing advancements in gene therapy and pharmaceutical applications.

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