Lulu Liu

Title: Innovations of Lulu Liu in DNA Recognition

Introduction

Lulu Liu is a prominent inventor based in Beijing, China. She has made significant contributions to the field of molecular biology, particularly in the area of DNA recognition and modification. Her work focuses on the development of innovative tools for gene editing and detection.

Latest Patents

Lulu Liu holds a patent titled "Tale RVD specifically recognizing DNA base modified by methylation and application thereof." This invention identifies RVDs with recognition preferences for 5mC, 5hmC, and 6 mA, showcasing different binding properties to these epigenetic modifications. The patent outlines methods for methylation-dependent gene activation, efficient genome editing, and targeted detection of 5hmC. The invention provides an isolated DNA binding polypeptide containing TALEs, a fusion protein, a polynucleotide, a vector comprising the polynucleotide, and a host cell. It also details the use of the protein comprising TALE repeats domain in preparing a reagent for detecting a methylated base in a target sequence of a gene of interest.

Career Highlights

Lulu Liu has worked at prestigious institutions, including Peking University and Edigene Inc. Her experience in these organizations has allowed her to advance her research and contribute to significant scientific advancements.

Collaborations

Lulu Liu has collaborated with notable colleagues, including Wensheng Wei and Chengqi Yi. These partnerships have further enriched her research and innovation in the field.

Conclusion

Lulu Liu's contributions to DNA recognition and modification represent a significant advancement in molecular biology. Her innovative patent and collaborations highlight her role as a leading inventor in this critical area of research.