Company Filing History:
Years Active: 2018-2019
Title: The Innovative Journey of Lisa Marx in the Field of Asymmetric Synthesis
Introduction
Lisa Marx, an adept inventor from Seeheim-Jugenheim, Germany, has contributed significantly to the field of asymmetric synthesis. She holds two patents that showcase her innovative approach to enzyme engineering and biochemical synthesis, specifically in the production of (S)-phenylacetylcarbinol.
Latest Patents
Marx's latest patents include groundbreaking work on a lyase and methods for the asymmetric synthesis of (S)-phenylacetylcarbinol. Her first patent details a lyase containing specific amino acid modifications. In this invention, Isoleucine at position 468 in the ApPDC-E469G protein is replaced with a less space-filling amino acid. This modification enhances the lyase's effectiveness in catalyzing the synthesis of (S)-phenylacetylcarbinol.
The second patent by Marx elaborates on a similar lyase and its encoding DNA. In this case, Tryptophan at position 543 is substituted with another amino acid, allowing for improved synthesis capabilities. This lyase can efficiently produce (S)-phenylacetylcarbinol from benzaldehyde and pyruvate or acetaldehyde, achieving an impressive enantiomeric excess of at least 94%.
Career Highlights
Lisa Marx's career is closely linked with Forschungszentrum Juelich GmbH, where she pursues her research in biochemical innovations. Her expertise in lyase engineering positions her as a valuable asset to her company and the scientific community.
Collaborations
Throughout her career, Lisa has collaborated with experienced colleagues such as Doerte Rother and Martina Pohl. These collaborations foster a creative environment, leading to productive advancements in their shared field of research.
Conclusion
Lisa Marx exemplifies the spirit of innovation in the biochemistry arena with her contributions to asymmetric synthesis. Her patents not only highlight her technical skills but also affirm her commitment to advancing scientific knowledge. As part of her team at Forschungszentrum Juelich GmbH, Lisa continues to pave the way for further breakthroughs in enzyme engineering and biocatalysis.