Lino Tessarollo

Title: **The Innovative Contributions of Lino Tessarollo in Genetic Research**

Introduction

Lino Tessarollo is an accomplished inventor based in Frederick, MD, whose work has significantly impacted the field of genetics. With a focus on developing methods to address the von Hippel-Lindau (VHL) disease, his contributions are noteworthy in advancing biomedical research.

Latest Patents

Mr. Tessarollo holds a patent for a model targeting the von Hippel-Lindau disease. This innovation includes nucleic acid molecules that facilitate the loss of function of the VHL allele in both somatic and germ cells. Furthermore, his patent outlines methods for utilizing these molecules to engineer conditional VHL gene-targeted and conditional VHL knockout animals. These conditional VHL gene target vectors, when inserted into the endogenous VHL gene, can lead to the deletion of an exon in the VHL gene through site-specific recombination upon conditional expression of a recombinase.

Career Highlights

Lino Tessarollo is affiliated with the United States Department of Health and Human Services, where he continues to refine his research on genetic diseases. His work has garnered attention for its potential applications in understanding and treating VHL disease, a hereditary condition that increases the risk of certain tumors.

Collaborations

Throughout his career, Mr. Tessarollo has collaborated with several esteemed professionals, including Laura S. Schmidt and Wenbin Ma. These partnerships enhance the interdisciplinary approach necessary for tackling complex medical challenges.

Conclusion

Lino Tessarollo's innovative work in the realm of genetic research exemplifies the role of inventors in advancing medical science. His patented methodologies not only contribute to the understanding of VHL disease but also pave the way for future innovations in gene therapy and genetic engineering.