Lindsey E McQuade

Title: Lindsey E McQuade: Innovator in Bacterial Nitric Oxide Synthase Inhibition

Introduction

Lindsey E McQuade is a prominent inventor based in Union City, CA (US). She has made significant contributions to the field of biochemistry, particularly in the development of compounds that target bacterial nitric oxide synthase (bNOS). Her innovative work has the potential to advance the understanding and treatment of various bacterial infections.

Latest Patents

Lindsey holds a patent for her invention titled "Inhibitors of bacterial nitric oxide synthase, and related screening methods." This invention relates to compounds that act as highly nitric oxide (NO)-specific turn-on fluorescent probes. The technology allows for the selective screening of inhibitors of bNOS, enabling researchers to detect nitric oxide produced in vivo. The fluorescein-based sensors developed in her patent can be utilized in assays that measure NO production by bNOS, facilitating the screening of libraries of small molecules for potential inhibitors.

Career Highlights

Lindsey E McQuade has established herself as a key figure in her field through her innovative research and patent contributions. She is affiliated with the Massachusetts Institute of Technology, where she continues to explore the applications of her inventions in the scientific community.

Collaborations

Throughout her career, Lindsey has collaborated with notable scientists, including Stephen J Lippard and Evgeny A Nudler. These collaborations have further enriched her research and expanded the impact of her work in the field of biochemistry.

Conclusion

Lindsey E McQuade's contributions to the development of inhibitors for bacterial nitric oxide synthase highlight her innovative spirit and dedication to advancing scientific knowledge. Her work not only enhances our understanding of bacterial infections but also opens new avenues for therapeutic interventions.