Company Filing History:
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Years Active: 2021-2025
Title: The Innovative Contributions of Lenka Van Sint Fiet
Introduction
Lenka Van Sint Fiet is a prominent inventor based in Leiden, Netherlands. She has made significant contributions to the field of RNA editing, particularly in the context of genetic disorders. With a total of eight patents to her name, her work is paving the way for new therapeutic approaches.
Latest Patents
Among her latest patents is the invention of RNA-editing oligonucleotides for the treatment of Usher syndrome. This invention focuses on oligonucleotides that can specifically edit a target nucleotide, adenine, in a target RNA molecule within eukaryotic cells. The oligonucleotide is designed for use in treating Usher syndrome, specifically targeting premature stop codons in the USH2A pre-mRNA or mRNA. Another notable patent involves chemically modified single-stranded RNA-editing oligonucleotides. This invention relates to antisense oligonucleotides that can edit a target nucleotide in a target RNA sequence without forming an intramolecular hairpin or stem-loop structure.
Career Highlights
Lenka has worked with notable organizations such as ProQR Therapeutics and the University of Rochester. Her experience in these institutions has allowed her to advance her research and contribute to innovative solutions in genetic therapies.
Collaborations
Throughout her career, Lenka has collaborated with esteemed colleagues, including Janne Juha Turunen and Bart Klein. These partnerships have enriched her research and expanded the impact of her inventions.
Conclusion
Lenka Van Sint Fiet's work in RNA editing is a testament to her innovative spirit and dedication to advancing medical science. Her patents not only highlight her expertise but also offer hope for new treatments for genetic disorders.