Lexington, KY, United States of America

Lei Fang


Average Co-Inventor Count = 3.0

ph-index = 1


Company Filing History:


Years Active: 2018

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1 patent (USPTO):Explore Patents

Title: Lei Fang: Innovating Cocaine Hydrolysis for Medical Applications

Introduction

Lei Fang, a distinguished inventor based in Lexington, KY, has made significant contributions to the field of biochemistry through his innovative research. With one patent to his name, his work focuses on enhancing the metabolism of cocaine, providing potential avenues for medical treatment.

Latest Patents

Lei Fang's notable patent, titled "High activity mutants of cocaine esterase for cocaine hydrolysis," presents bacterial cocaine esterase (CocE) mutants that exhibit enhanced catalytic efficiency for (-)-cocaine. Compared to previous mutants, including CocE mutant E172-173, these newly disclosed variants offer improved performance in cocaine hydrolysis. The patent also encompasses a pharmaceutical composition containing a mutant of bacterial cocaine hydrolase alongside a suitable pharmaceutical carrier. A significant aspect of this invention is its application in treating cocaine-induced conditions by administering an effective amount of the mutant to accelerate cocaine metabolism, thereby producing biologically inactive metabolites.

Career Highlights

Lei Fang is affiliated with the University of Kentucky Research Foundation, where he has conducted his pioneering research. His experience and expertise have contributed to advancements in the understanding and treatment of cocaine-related disorders.

Collaborations

Throughout his career, Lei Fang has collaborated with esteemed colleagues, including Chang-Guo Zhan and fellow inventor Fang Zheng, who has also made noteworthy contributions in their respective fields. These partnerships emphasize the collaborative nature of scientific research, allowing for the pooling of knowledge and resources.

Conclusion

With his innovative approach to cocaine hydrolysis and a commitment to advancing medical treatments, Lei Fang stands out as a key figure in the realm of biochemistry. His patent not only reflects his inventiveness but also sheds light on the potential for developing effective therapies for addiction-related conditions. As the field continues to evolve, inventors like Lei Fang play a critical role in driving progress and improving patient outcomes.

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