Laura Da Silva

Title: Innovations of Laura Da Silva

Introduction

Laura Da Silva is a prominent inventor based in Charvieu, France. She has made significant contributions to the field of polynucleic acid synthesis, holding 2 patents that showcase her innovative methods. Her work is characterized by a focus on non-enzymatic processes, which have the potential to advance biotechnological applications.

Latest Patents

One of Laura Da Silva's latest patents involves a method for synthesizing polynucleic acids. This method includes several steps: first, providing an acidic solution that is substantially free of nucleic acid polymerase and lipids, while containing mononucleotides and a monovalent salt. The mixture is then dried and resolubilized multiple times, followed by the recovery of polynucleic acids from the resolubilized mixture. The method can utilize low pH conditions, such as around 3, and can employ monophosphates like AMP instead of ATP. This innovative approach allows for the formation of both single-stranded and double-stranded polynucleic acids. Notably, ammonia salts have been used to achieve RNA lengths ranging from 10 to 300 nucleotides after 16 half-hour cycles, with effective temperatures between 80°C and 100°C.

Career Highlights

Throughout her career, Laura Da Silva has worked with esteemed institutions, including the University of California and Sorbonne Université. Her research has contributed to the understanding and development of polynucleic acid synthesis techniques, positioning her as a key figure in her field.

Collaborations

Laura has collaborated with notable individuals such as David W. Deamer and Marie-Christine Maurel. These partnerships have further enriched her research and innovation efforts.

Conclusion

Laura Da Silva's work in the synthesis of polynucleic acids represents a significant advancement in biotechnology. Her innovative methods and collaborations highlight her contributions to the scientific community.