Company Filing History:
Years Active: 1993-2001
Title: Innovations by Larry D. Henry in Monoclonal Antibodies
Introduction
Larry D. Henry is a notable inventor based in Brookline, MA, who has made significant contributions to the field of immunology through his innovative work on monoclonal antibodies. With a total of five patents to his name, his inventions have advanced the understanding and application of T cell antigen receptors.
Latest Patents
Henry's latest patents focus on monoclonal antibodies that react with defined regions of the T cell antigen receptor (TCR). One of his key inventions provides monoclonal antibodies that recognize a constant region of the alpha chain of the TCR. Specifically, he has developed two monoclonal antibodies, termed αF1 and αF2, which target different epitopes on the framework region of the alpha monomer of the TCR molecule. Additionally, he has created monoclonal antibodies that react with variable regions of the beta chain of the TCR, including W112 and 2D1, which interact with β chain variable regions Vβ5.3 and Vβ8.1, respectively. Furthermore, his work includes monoclonal antibody δTCS1, isotype IgG2a, which targets a variable region of the delta chain of the TCR. These monoclonal antibodies hold significant value in both diagnosis and therapy, serving as essential tools for studying the immune system.
Career Highlights
Throughout his career, Larry D. Henry has worked with prominent companies in the biotechnology sector, including Astra Ab and T Cell Sciences, Inc. His expertise in monoclonal antibodies has positioned him as a key figure in the development of innovative therapeutic solutions.
Collaborations
Henry has collaborated with notable professionals in his field, including Robert V. Skibbens and Charles William Rittershaus. These partnerships have further enhanced the impact of his research and inventions.
Conclusion
Larry D. Henry's contributions to the field of immunology through his patents on monoclonal antibodies demonstrate his innovative spirit and commitment to advancing medical science. His work continues to influence the study and treatment of immune-related conditions.