Kristina A Cole

Title: Innovations of Kristina A Cole in Prostate Cancer Research

Introduction

Kristina A Cole is an accomplished inventor based in Swarthmore, PA (US). She has made significant contributions to the field of cancer research, particularly in understanding the genetic factors associated with prostate cancer. Her work has led to the identification of novel genes that may play a crucial role in the diagnosis and treatment of this disease.

Latest Patents

Kristina A Cole holds a patent for her invention titled "PB 39, a gene dysregulated in prostate cancer, and uses thereof." This patent describes a novel gene, PB39, which is up-regulated in prostate cancer. The gene was identified through cDNA obtained by reverse transcription of the corresponding mRNA. Her research involved microdissection of prostate glands surgically removed from patients, revealing a significant up-regulated transcript in aggressive prostate carcinoma. The invention provides a purified and isolated nucleic acid that includes the sequence of PB39 or its complement, as well as methods for detecting PB39 or its gene product.

Career Highlights

Kristina A Cole is affiliated with the National Institutes of Health, a component of the US Department of Health & Human Services. Her work at this prestigious institution has allowed her to focus on groundbreaking research in cancer genetics. She has been instrumental in advancing our understanding of the molecular mechanisms underlying prostate cancer.

Collaborations

Throughout her career, Kristina has collaborated with notable colleagues, including Rodrigo F Chuaqui and Lance A Liotta. These collaborations have further enriched her research and contributed to the advancement of cancer diagnostics.

Conclusion

Kristina A Cole's innovative work in identifying the PB39 gene highlights her significant contributions to prostate cancer research. Her patent and ongoing research efforts continue to pave the way for advancements in cancer diagnostics and treatment.