Company Filing History:
Years Active: 2010
Title: Kieron Brown - Innovator in Molecular Structures
Introduction
Kieron Brown is a notable inventor based in Abingdon, GB. He has made significant contributions to the field of molecular biology, particularly in the study of polo-like kinase 3 (PLK3). His innovative work has implications for drug design and protein structure analysis.
Latest Patents
Kieron Brown holds a patent for the "Crystal structure of polo-like kinase 3 (PLK3) and binding pockets thereof." This invention relates to molecules or molecular complexes that comprise binding pockets of PLK3 or its structural homologues. The patent details crystallizable compositions and crystals that include PLK3. Additionally, it encompasses a data storage medium encoded with the structural coordinates of these molecules and complexes. The invention also describes a computer that can generate a three-dimensional structure or graphical representation of such molecules. Furthermore, it outlines methods for using the structure coordinates to solve the structures of homologous proteins or protein complexes, as well as to screen for and design compounds that bind to PLK3 or its homologues.
Career Highlights
Kieron Brown is currently associated with Vertex Pharmaceuticals, Inc., where he continues to advance his research in molecular structures. His work is pivotal in understanding the mechanisms of PLK3 and its potential as a therapeutic target.
Collaborations
Kieron has collaborated with esteemed colleagues such as Graham M T Cheetham and Suzanne B Renwick. Their combined expertise enhances the research and development efforts in their field.
Conclusion
Kieron Brown's innovative contributions to the understanding of PLK3 and its binding pockets represent a significant advancement in molecular biology. His work not only furthers scientific knowledge but also opens new avenues for therapeutic development.