Company Filing History:
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Years Active: 1998-2000
Title: Innovations in Genetic Research: The Contributions of Keith D. Harshman
Introduction
Keith D. Harshman, located in Salt Lake City, Utah, is a distinguished inventor in the field of human genetics. With a remarkable portfolio of four patents, Harshman's work primarily focuses on the genetic factors related to breast and ovarian cancer. His contributions have significantly advanced the understanding and diagnosis of cancer susceptibility genes, particularly the BRCA1 gene.
Latest Patents
Harshman's latest patents involve groundbreaking research associated with the BRCA1 gene, a critical factor in breast and ovarian cancer susceptibility. The first patent details methods and materials for isolating and detecting mutations in the BRCA1 gene, particularly germline and somatic mutations that correlate with an increased risk of developing these cancers. This invention not only aids in diagnosing predisposition to breast and ovarian cancer but also encompasses the therapeutic approaches for cancers caused by mutations in the BRCA1 gene. These therapeutic methods include gene therapy, protein replacement therapy, and the development of protein mimetics, alongside drug screening techniques that target these mutations for cancer treatment.
Career Highlights
Throughout his career, Keith D. Harshman has made significant strides in genetic research, particularly during his tenure at the University of Utah Research Foundation and Myriad Genetics, Inc. His innovative approach to understanding cancer genetics has positioned him as a key figure in the field, contributing to vital research that can potentially save lives.
Collaborations
In his professional journey, Harshman has collaborated with notable scientists like Mark H. Skolnick and David E. Goldgar. Their combined expertise has propelled advancements in genetic research, particularly in isolating and identifying cancer susceptibility genes.
Conclusion
Keith D. Harshman’s contributions to the field of human genetics, particularly concerning the BRCA1 gene, have paved the way for more accurate diagnosis and treatment options for breast and ovarian cancers. His innovative spirit and collaborations with leading researchers underscore the importance of continued research in understanding genetic factors related to cancer susceptibility. Harshman's work exemplifies the intersection of innovation and medical advancement, highlighting the critical role of inventors in changing the landscape of healthcare.