Company Filing History:
Years Active: 2001-2004
Title: Kazushi Inoue: Innovator in Transcription Factor Research
Introduction
Kazushi Inoue is a prominent inventor based in Memphis, TN (US). He has made significant contributions to the field of molecular biology, particularly in the study of transcription factors and their interactions with cyclins. With a total of 3 patents, Inoue's work has implications for understanding gene regulation.
Latest Patents
One of Inoue's latest patents is titled "Cyclin D binding factor, and uses thereof." This invention discloses a direct interaction between D-type cyclins and a novel myb-like transcription factor known as DMP1. DMP1 specifically interacts with cyclin D2, providing evidence that D-type cyclins can regulate gene expression in an RB-independent manner. The invention includes amino acid sequences coding for DMP1, as well as DNA and RNA nucleotide sequences that encode these amino acids. Furthermore, DMP1 has been shown to activate the transcription of a reporter gene when transfected into mammalian cells, highlighting its potential as a transcription factor.
Career Highlights
Kazushi Inoue is affiliated with St. Jude Children's Research Hospital, where he conducts his research. His work has been instrumental in advancing the understanding of transcription factors and their roles in cellular processes.
Collaborations
Inoue has collaborated with notable colleagues, including Charles J Sherr and Hiroshi Hirai. These collaborations have further enriched his research and contributed to the scientific community's knowledge in the field.
Conclusion
Kazushi Inoue's innovative research and patents in the area of transcription factors and cyclin interactions underscore his importance in molecular biology. His contributions continue to influence the understanding of gene regulation and its implications for health and disease.