Katsumi Hotoda

Title: Katsumi Hotoda: Innovator in Pharmaceutical Crystallization

Introduction

Katsumi Hotoda is a notable inventor based in Edogawa-ku, Japan. He has made significant contributions to the field of pharmaceuticals, particularly in the production of specific crystal forms of important compounds. His work has implications for drug formulation and stability.

Latest Patents

Katsumi Hotoda holds a patent for a method titled "Method for producing alpha form crystals of sapropterin hydrochloride." This innovative method allows for the selective production of stable alpha form crystals of sapropterin hydrochloride. The process involves dissolving sapropterin hydrochloride with hydrochloric acid at a concentration of not less than 4 mol/L at temperatures exceeding 70 degrees Celsius. Following this, heated ethanol is added to the solution, and the solution is cooled at a rate not faster than 3 degrees Celsius per minute to a temperature range of 40 to 55 degrees Celsius, resulting in the precipitation of the desired crystals. He has 1 patent to his name.

Career Highlights

Throughout his career, Katsumi Hotoda has worked with prominent companies in the pharmaceutical industry. Notably, he has been associated with Shiratori Pharmaceutical Co., Ltd. and Daiichi Sankyo Company, Limited. His expertise in crystallization techniques has been instrumental in advancing pharmaceutical formulations.

Collaborations

Katsumi Hotoda has collaborated with esteemed colleagues, including Hiroomi Kiyono and Shinnosuke Tazawa. These collaborations have contributed to the development of innovative solutions in the pharmaceutical sector.

Conclusion

Katsumi Hotoda's contributions to the field of pharmaceutical crystallization highlight his role as an innovator. His patented method for producing alpha form crystals of sapropterin hydrochloride showcases his expertise and commitment to advancing pharmaceutical science.