This inventor holds 2 USPTO granted patents and 5 published patent applications. Top assignee: The Perkin-Elmer Corporation. Active years: 2000.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2000
Title: Innovations of Katherine D Lazaruk
Introduction
Katherine D Lazaruk is a notable inventor based in Redwood City, CA (US). She has made significant contributions to the field of biotechnology, particularly in the development of novel oligonucleotides. With a total of 2 patents, her work has advanced methods in DNA sequencing and nucleic acid amplification.
Latest Patents
Katherine's latest patents include the invention of phosphoramidate-phosphodiester oligonucleotide chimeras. These innovative chimeric phosphoramidate oligonucleotides feature both N3'-phosphoramidate linkages and phosphodiester linkages. The invention encompasses methods of primer extension using these chimeric oligonucleotides as primers. Notably, the primer extension methods are applicable in nucleic acid amplification reactions, such as PCR, and in polynucleotide sequencing reactions. The chimeric oligonucleotide primer is designed to anneal to a polynucleotide template, followed by extension through a DNA polymerase catalyzed reaction. The invention also includes compositions that enhance the binding affinity between the chimeric oligonucleotides and polynucleotide templates, utilizing divalent cations to stabilize the phosphoramidate linkages against hydrolysis at elevated temperatures.
Career Highlights
Throughout her career, Katherine has worked with reputable organizations, including the Perkin-Elmer Corporation. Her experience in these companies has contributed to her expertise in the field of biotechnology and oligonucleotide research.
Collaborations
Katherine has collaborated with notable colleagues such as Nicole M Ellis and Robert G Kuimelis. These partnerships have likely enriched her research and development efforts in her innovative projects.
Conclusion
Katherine D Lazaruk's contributions to the field of biotechnology through her innovative patents and collaborations highlight her role as a significant inventor. Her work continues to influence advancements in DNA sequencing and nucleic acid amplification methods.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile