Company Filing History:
Years Active: 2025
Title: Katherine Coombs: Innovator in Contractile Force Measurement
Introduction
Katherine Coombs is an accomplished inventor based in Oaklyn, NJ (US). She has made significant contributions to the field of biomedical engineering, particularly in the measurement of contractile forces in cells and tissues. Her innovative approach has the potential to enhance our understanding of cellular mechanics and improve various applications in tissue engineering.
Latest Patents
Katherine holds a patent for an in-vitro contractile force indicator. This device and its associated methods are designed to measure the contractile force exerted by cells and tissues. The invention includes a mount with both rigid and non-rigid posts that are sized to flex. The device is specifically designed to fit inside individual wells of a multiwell plate, allowing for precise measurements. As the hydrogel condenses, the cells or tissue wrap around the non-rigid post, pulling it toward the rigid post. An inverted light microscope is utilized to determine the deflection of the non-rigid post, and the movement is measured using an acrylic ruler positioned on the underside of the multiwell plate. The contractile forces are calculated using cantilever mechanics, providing valuable insights into cellular behavior.
Career Highlights
Katherine Coombs is affiliated with the New Jersey Institute of Technology, where she continues to advance her research and innovations. Her work has garnered attention for its practical applications in understanding cellular dynamics and improving tissue engineering techniques.
Collaborations
Katherine collaborates with notable colleagues, including Jonathan Grasman and Jessica Pridmore. Their combined expertise contributes to the advancement of research in the field of biomedical engineering.
Conclusion
Katherine Coombs is a pioneering inventor whose work in contractile force measurement is paving the way for advancements in biomedical research. Her innovative patent and collaborations highlight her commitment to enhancing our understanding of cellular mechanics.