Company Filing History:
Years Active: 2003-2007
Title: Karen Kulju McKee: Pioneering Innovations in Receptor Biology
Introduction
Karen Kulju McKee, based in Middletown, NJ, is a distinguished inventor known for her significant contributions to the field of receptor biology. With a remarkable portfolio that includes three patents, her work focuses on advancements that hold promise for treating various gastric and hormonal conditions.
Latest Patents
Karen's latest inventions include groundbreaking research on two distinct receptors:
1. **Cloning and Identification of the Motilin Receptor** - In this project, the motilin receptor has been isolated and cloned, with relevant nucleic acid sequences provided. Two splice variants have been identified, alongside assays for motilin receptor ligands. The cloned motilin receptor may serve as a valuable tool to screen and identify compounds that bind to it, which can be instrumental in addressing various gastric motility disorders.
2. **Mouse Growth Hormone Secretagogue Receptor** - This patent highlights the isolation, cloning, and sequencing of a mouse growth hormone secretagogue receptor, which is characterized as part of the G-protein family of receptors. The implications of this research extend to screening for compounds binding to the receptor, potentially aiding in the treatment of conditions linked to growth hormone deficiencies, including issues in growth hormone-deficient children and elderly patients recovering from musculoskeletal impairments.
Career Highlights
Karen Kulju McKee is currently employed at Merck & Company, Inc., where she applies her extensive knowledge to innovative research. Her work has not only contributed to the scientific community but has also paved the way for therapeutic advancements in medicine.
Collaborations
Throughout her career, Karen has collaborated with notable colleagues, including Andrew D. Howard and Roy G. Smith. Their combined expertise has further enriched the research projects they have undertaken, resulting in impactful findings within their field.
Conclusion
In conclusion, Karen Kulju McKee's pioneering efforts in receptor biology exemplify the critical role that inventors play in driving innovation forward. Her patents reflect a commitment to enhancing healthcare through scientific discovery, and her ongoing work promises to contribute further to our understanding and treatment of various medical conditions.