Location History:
- Bengaluru, IN (2008)
- Ellicot City, MD (US) (2008)
- Ellicott City, MD (US) (2010)
Company Filing History:
Years Active: 2008-2010
Title: Innovations by Karanam Balasubramanyam
Introduction
Karanam Balasubramanyam is an accomplished inventor based in Ellicott City, MD (US). He holds three patents that contribute significantly to the field of biochemistry, particularly in the area of cancer research and gene regulation.
Latest Patents
His latest patents include "Modulators (inhibitors/activators) of histone acetyltransferases." This invention provides the use of certain benzoic acid and benzamide compounds as modulators of enzymes histone acetyltransferases, which are involved in gene expression and cancer. The invention also discusses the use of such compounds in the treatment of diseases due to defects in gene regulation, predominantly cancer.
Another notable patent is "Polyisoprenylated benzophenones and their isomers as inhibitors of histone acetyltransferases and uses thereof." In this patent, he describes the purification of prenylated benzophenones from the fruit rinds of specific species and evaluates them as inhibitors for histone acetyltransferases p300 and PCAF. The findings indicate that prenylated benzophenones are potent HAT inhibitors of p300 and PCAF. These inhibitors significantly repress the p300 HAT dependent transcriptional activation from in vitro assembled chromatin templates but have no effect on transcription from DNA. This suggests that the compounds could be specific to HATs and may serve as new chemical entities for the development of anticancer drugs.
Career Highlights
Karanam Balasubramanyam is affiliated with the Jawaharlal Nehru Centre for Advanced Scientific Research, where he conducts his research and develops his innovative ideas. His work has garnered attention for its potential applications in cancer treatment and gene regulation.
Collaborations
He collaborates with notable colleagues such as Tapas Kumar Kundu and Venkatesh Swaminathan, contributing to a dynamic research environment that fosters innovation.
Conclusion
Karanam Balasubramanyam's contributions to the field of biochemistry through his patents highlight his commitment to advancing cancer research and gene regulation. His work exemplifies the impact of innovative thinking in scientific research.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.