Company Filing History:
Years Active: 2021
Title: Kaja Fac-Dąbrowska: Innovator in mRNA Technology
Introduction
Kaja Fac-Dąbrowska is a prominent inventor based in Warsaw, Poland. She has made significant contributions to the field of molecular biology, particularly in the development of mRNA technologies. Her innovative work focuses on enhancing the stability and translational activity of mRNA, which has important implications for therapeutic applications.
Latest Patents
Kaja Fac-Dąbrowska holds a patent for "5'-phosphorothiolate mRNA 5′-end (cap) analogs, mRNA comprising the same, method of obtaining and uses thereof." This invention relates to nucleotides and mRNA 5'-end analogs that contain a sulfur atom at the position 5′ of 7-methylguanosine nucleoside. The disclosed compounds are recognized by the DcpS enzyme, which is a cap-specific enzyme with pyrophosphatase activity. This invention may serve as a therapeutic target in the treatment of spinal muscular atrophy (SMA). The compounds also feature modifications in the phosphate chain that enhance their affinity for the DcpS enzyme.
Career Highlights
Kaja is affiliated with the University of Warsaw, where she conducts her research and development activities. Her work has garnered attention for its potential to revolutionize mRNA therapies. With a focus on creating more effective mRNA formulations, she is paving the way for advancements in genetic medicine.
Collaborations
Kaja collaborates with notable colleagues, including Jacek Jemielity and Blażej Wojtczak. Their combined expertise contributes to the innovative research being conducted at the University of Warsaw.
Conclusion
Kaja Fac-Dąbrowska is a trailblazer in the field of mRNA technology, with her patent holding promise for future therapeutic applications. Her contributions to molecular biology are significant and continue to influence the landscape of genetic medicine.