Justin Lee

Title: Innovations by Justin Lee in T-cell Immunotherapy

Introduction

Justin Lee is an innovative inventor based in Pasadena, CA. He has made significant contributions to the field of immunotherapy, particularly in the thermal control of T-cells. His work focuses on enhancing the effectiveness of T-cell therapies through advanced methodologies.

Latest Patents

Justin Lee holds a patent for "Thermal control of T-cell immunotherapy through molecular and physical actuation." This patent discloses methods, compositions, and kits that are suitable for spatiotemporal regulation of therapeutic T-cells. The invention includes thermal bioswitches that enable T-cells to sense small temperature changes, which serve as inputs for the actuation of genetic circuits. Additionally, the patent covers T-cell activity sensors and genetic circuits that induce expression of a payload upon thermal stimulation or immune cell stimulation. The invention also provides thermally actuated immune cells and methods for their use, along with oscillator circuits and methods to prevent T-cell exhaustion.

Career Highlights

Justin Lee is affiliated with the California Institute of Technology, where he continues to advance research in immunotherapy. His work is pivotal in developing innovative solutions that enhance the functionality of T-cells in therapeutic applications.

Collaborations

Justin collaborates with notable colleagues, including Mohamad H Abedi and Mikhail G Shapiro. Their combined expertise contributes to the advancement of research in the field of immunotherapy.

Conclusion

Justin Lee's innovative work in T-cell immunotherapy represents a significant advancement in the field. His patent and ongoing research have the potential to transform therapeutic approaches and improve patient outcomes.