Company Filing History:
Years Active: 2013-2024
Title: Joseph Brian Hiatt: Innovator in DNA Sequencing Technologies
Introduction
Joseph Brian Hiatt is a prominent inventor based in Seattle, WA (US), known for his significant contributions to the field of DNA sequencing. With a total of 11 patents to his name, Hiatt has made remarkable advancements that enhance the efficiency and accuracy of genomic research.
Latest Patents
Among his latest patents is a method titled "Sequence tag directed subassembly of short sequencing reads into long sequencing reads." This innovative approach focuses on preparing a DNA sequencing library that optimally brings distal fragmentation breakpoints into close proximity to the non-degenerate sequence tag. The method involves circularizing a target fragment library with a variety of adaptor molecules, producing a population of first circularized double-stranded DNA molecules. This technique is particularly beneficial for sequencing platforms that perform best with shorter template molecules, typically less than 500 base pairs in length.
Another notable patent is "Massively parallel contiguity mapping," which addresses the importance of contiguity information in achieving high-quality de novo assembly of mammalian genomes. The methods outlined in this patent aim for cost-effective, massively parallel capture of contiguity information at various scales, which is crucial for haplotype-resolved resequencing of human genomes.
Career Highlights
Joseph Brian Hiatt is affiliated with the University of Washington, where he continues to push the boundaries of genomic research through his innovative work. His career is marked by a commitment to developing technologies that facilitate advancements in DNA sequencing and genomic analysis.
Collaborations
Hiatt has collaborated with notable colleagues such as Jay Ashok Shendure and Rupali Patwardhan, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Joseph Brian Hiatt stands out as a key figure in the field of DNA sequencing, with his patents reflecting a deep understanding of genomic technologies. His work not only advances scientific knowledge but also enhances the capabilities of genomic research, paving the way for future innovations.