Jonathan Grasman

Title: The Innovative Contributions of Jonathan Grasman

Introduction

Jonathan Grasman is an accomplished inventor based in West Orange, NJ (US). He has made significant strides in the field of biomedical engineering, particularly with his innovative device designed to measure the contractile forces of cells and tissues. His work is pivotal in advancing our understanding of cellular mechanics.

Latest Patents

Grasman holds a patent for an "In-vitro contractile force indicator." This device and its associated methods are designed to measure the contractile force exerted by cells and tissues in a multiwell plate. The invention includes a mount with both rigid and non-rigid posts that are sized to flex. The device is specifically designed to fit inside individual wells, with posts directed downwards. The mount features a window for medium changes while the device remains positioned inside the well. Cells are seeded within a hydrogel, and as the hydrogel condenses, the cells or tissue wrap around the non-rigid post, pulling it toward the rigid post. An inverted light microscope is utilized to determine the deflection of the non-rigid post inside the multiwell plate. The movement of the non-rigid post is measured using an acrylic ruler located on the underside of the multiwell plate. The contractile forces of the cells and tissue are determined using cantilever mechanics. Grasman's innovative approach has the potential to enhance research in cellular dynamics.

Career Highlights

Grasman is affiliated with the New Jersey Institute of Technology, where he contributes to research and development in the field of biomedical engineering. His work is characterized by a commitment to innovation and a focus on practical applications that can benefit scientific research and medical practices.

Collaborations

Grasman collaborates with talented colleagues, including Jessica Pridmore and Cassandra Martin. Their combined expertise fosters a productive research environment that encourages the development of groundbreaking technologies.

Conclusion

Jonathan Grasman exemplifies the spirit of innovation in the field of biomedical engineering. His patent for the in-vitro contractile force indicator represents a significant advancement in measuring cellular mechanics. Through his work at the New Jersey Institute of Technology and collaborations with fellow researchers, Grasman continues to contribute to the scientific community and push the boundaries of what is possible in biomedical research.