Location History:
- Palo Alto, CA (US) (1985 - 1988)
- Los Altos, CA (US) (1996)
- Los Altos Hills, CA (US) (1990 - 2000)
Company Filing History:
4 out of 932 
3 out of 165 
1 out of 1 Years Active: 1985-2000
Title: Innovator Spotlight: Jonathan Briggs of Palo Alto, CA
Introduction: Jonathan Briggs is a notable inventor based in Palo Alto, California, renowned for his contributions to the field of nucleic acid sequencing. With a total of nine patents to his name, Briggs has demonstrated significant advancements in molecular biology techniques, making a lasting impact on genetic research and biotechnology.
Latest Patents: Among his latest innovations is the patent for a "Method of sequencing nucleic acids by shift registering." This groundbreaking invention describes a novel technique for sequencing nucleic acids using mixtures of oligonucleotide fragments derived from sequencing reactions. The method utilizes 2',3'-dideoxynucleoside 5'-triphosphate or 3' deoxynucleoside 5'-triphosphate terminators combined with appropriate concentrations of dNTPs. Notably, it separates itself from traditional slab gel sequencing methods by avoiding the need for precise alignment of terminated fragments, thereby facilitating easier sequence assignment even in the presence of uncertainties.
Another notable patent is the "Capillary electrophoresis apparatus and method," which innovatively addresses multiplexing electrophoresis analysis. This invention allows for simultaneous processing of multiple samples in multi-well plates, enhancing efficiency in DNA analysis, sequencing, and studying reactions involving specifically binding proteins.
Career Highlights: Jonathan Briggs has held pivotal roles in esteemed companies such as Syntex Inc. and Molecular Devices Corporation. His contributions in these organizations have been influential in the development of new technologies related to genetic sequencing and analysis.
Collaborations: Throughout his career, Briggs has collaborated with esteemed colleagues including Randy M. McCormick and David W. Hoyt. These partnerships have fostered innovation and pushed the boundaries of research in molecular biology, further showcasing the collaborative spirit inherent in scientific discoveries.
Conclusion: Jonathan Briggs continues to be a driving force in the innovations surrounding genetic sequencing and analysis. His latest patents not only reflect his expertise but also pave the way for advancements in the field, significantly impacting genetic research and biotechnology. As his career progresses, the scientific community eagerly anticipates the future contributions he will undoubtedly make.