Johnny C Loke

Title: Innovations by Johnny C Loke

Introduction

Johnny C Loke is an accomplished inventor based in Nanuet, NY (US). He has made significant contributions to the field of cancer research, particularly in understanding the mechanisms of DNA repair and cancer metastasis. With a total of 6 patents, his work has the potential to impact cancer diagnostics and treatment.

Latest Patents

One of his latest patents focuses on methods and compositions for determining the functional activity of DNA double strand break repair pathway molecules. This innovation aims to assess the germline risk of cancer, particularly in relation to heritable mutations in the BRCA1 and BRCA2 genes. These mutations are known to increase the risk of breast, ovarian, and other cancers. The patent describes flow cytometry-based functional variant analyses (FVAs) that can distinguish high-risk BRCA1 mutations from low-risk controls. Another significant patent involves a robust genomic predictor of breast and lung cancer metastasis. This method determines the risk of metastasis by analyzing the number of copies per cell of specific genes in a sample from the subject.

Career Highlights

Johnny C Loke is affiliated with the Albert Einstein College of Medicine, where he conducts his research. His work is pivotal in advancing our understanding of cancer biology and improving patient outcomes through innovative diagnostic methods.

Collaborations

He has collaborated with notable colleagues such as Harry Ostrer and Alexander Pearlman, contributing to a rich environment of research and innovation.

Conclusion

Johnny C Loke's contributions to cancer research through his patents and collaborations highlight his role as a leading inventor in the field. His work continues to pave the way for advancements in cancer diagnostics and treatment strategies.