Location History:
- Bethesda, MD (US) (1995 - 1998)
- Kensington, MD (US) (1990 - 2001)
Company Filing History:
3 out of 1,217 
2 out of 3,446 
Years Active: 1990-2001
Title: The Innovations of John R. Ticehurst
Introduction
John R. Ticehurst is a notable inventor based in Kensington, MD, who has made significant contributions to the field of virology. He holds a total of five patents, primarily focused on vaccines against the hepatitis A virus. His work has been instrumental in advancing public health through innovative vaccine development.
Latest Patents
Ticehurst's latest patents include a vaccine against the hepatitis A virus, which provides an attenuated hepatitis A virus useful as a vaccine. Another significant patent is for a chimeric hepatitis A vaccine, which involves the construction of a full-length cDNA copy of an attenuated, cell culture-adapted hepatitis A virus genome. This innovation has led to the development of a plasmid designated pHAV/7, which, when transfected into monkey kidney cells, yields hepatitis A virus. The RNA transcripts produced from pHAV/7 result in a tenfold increase in virus yield, making it a valuable tool for vaccine production.
Career Highlights
Throughout his career, Ticehurst has worked with prominent organizations, including the United States of America as represented by the Department of Health and the National Institutes of Health, a component of the US Department of Health & Human Services. His work has had a lasting impact on vaccine research and development.
Collaborations
Ticehurst has collaborated with esteemed colleagues such as Robert H. Purcell and Jeffrey I. Cohen, contributing to the advancement of hepatitis A research.
Conclusion
John R. Ticehurst's innovative work in vaccine development has significantly contributed to the fight against hepatitis A. His patents and collaborations reflect his dedication to improving public health through scientific research.